Immatics is the global leader in precision targeting of PRAME

About us

Immatics has the broadest PRAME franchise with the most indications and therapeutic modalities.

Explore the pipeline

PRAME is expressed
in >50 cancers

PRAME is a target expressed in more than 50 cancers, including melanoma, lung, ovarian, breast, and endometrial cancer, among many others. Targeting PRAME unlocks new treatment options for a broad patient population with significant unmet medical need. To do so safely and effectively requires deep expertise in immunology, drug development and beyond.

Science explained

Clinical trials

Immatics is evaluating its targeted PRAME cell therapies and bispecific product candidates and actively enrolling patients in ongoing clinical trials.

Clinical trials

Press releases

Follow our progress as we advance PRAME therapies from lab to clinic and beyond.

17 July, 2026

Immatics Announces Upcoming Presentations Across Its PRAME Franchise at ESMO Congress 2026

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01 June, 2026

Immatics Presents Clinical Activity and Response Dynamics of Anzu-cel PRAME Cell Therapy at 2026 ASCO Annual Meeting

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31 May, 2026

Immatics Presents Data on IMA401 MAGEA4/8 Bispecific at 2026 ASCO Annual Meeting with Simultaneous Publication in Nature Medicine Supporting Development of IMA401/IMA402 Combination in Lung Cancer

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