Immatics is the Global Leader in Precision Targeting of PRAME

Immatics has the broadest PRAME franchise with the most indications and therapeutic modalities.

PRAME is expressed in >50 cancers

PRAME is a target expressed in more than 50 cancers, including melanoma, lung, ovarian, breast, and endometrial cancer, among many others. Targeting PRAME unlocks new treatment options for a broad patient population with significant unmet medical need. To do so safely and effectively requires deep expertise in immunology, drug development and beyond.

Clinical trials

Immatics is evaluating its targeted PRAME cell therapies and bispecific product candidates and actively enrolling patients in ongoing clinical trials.

Press releases

Follow our progress as we advance PRAME therapies from lab to clinic and beyond.

Immatics Presents IMA203CD8 PRAME Cell Therapy Data from Ongoing Dose Escalation and Shows Promising Initial Anti-tumor Activity in PRAME-Positive Tumors at ESMO-IO 2025 Congress
Immatics Announces $125 Million Underwritten Offering
Immatics Announces Third Quarter 2025 Financial Results and Business Update

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