Overview

Our purpose is to make
a difference for patients

Immatics is a clinical-stage biopharmaceutical company active in the discovery and development of T cell redirecting immunotherapies for the treatment of cancer. Immatics is sponsoring several clinical trials  to deliver the power of T cells to cancer patients. The purpose of these trials is to develop innovative immunotherapies aimed at targeting a patient’s tumor selectively and effectively.

We have a big goal: overcome the challenges of fighting cancer and bring new therapeutic products to cancer patients. We do this with a singular passion and relentless focus to achieve better outcomes for patients.

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Clinical
Trials

The following clinical trials are currently open and recruiting patients:

SUPRAME (NCT03686124) is a Phase 3, multicenter, open-label, randomized, actively controlled, parallel-group clinical trial to evaluate the efficacy, safety and tolerability of treatment with ACTengine® IMA203 administered at the recommended Phase 2 dose versus investigator’s choice of treatment in patients with previously treated, unresectable or metastatic cutaneous melanoma.

For more information on this clinical trial, click here

The IMA203-101 Phase 1 trial (NCT03686124) is evaluating the safety and tolerability of ACTengine® IMA203/IMA203CD8 products in patients with recurrent and/or refractory solid tumors that express PRAME (preferentially expressed antigen in melanoma).

For more information on this clinical trial, click here

The IMA401-101 Phase 1 trial (NCT05359445) is evaluating the safety, tolerability and initial anti-tumor activity of TCER® IMA401 in patients with recurrent and/or refractory solid tumors. TCER® IMA401 is a TCR Bispecific molecule that targets MAGEA4/8.

For more information on this clinical trial, click here

The IMA402-101 Phase 1 trial (NCT05958121) is evaluating safety, tolerability and anti-tumor activity of TCER® IMA402 in patients with recurrent and/or refractory solid tumors. TCER® IMA402 is a TCR Bispecific molecule that targets PRAME (preferentially expressed antigen in melanoma).

For more information on this clinical trial, click here

Patient
information

If you are a patient and interested participating in one of Immatics’ clinical trials, please speak to your treating physician.

To learn more about clinical trials, please click here.