Working @ Immatics

Senior Manufacturing Associate – 2nd Shift

Permanent employee, Full-time · Houston (TX)

Position Summary/objective:
The primary purpose of this position is to perform complex, highly specialized and time sensitive technical cell manipulation and testing procedures on irreplaceable cellular products during clinical manufacturing.
Your mission
Essential functions:
  • Fulfill the operator and verifier roles in performing cell growth and manipulation procedures such as cell enrichment, cell culture, cellular product cryopreservation, cell product thaw/wash.
  • Accurately perform procedures in compliance with FDA’s Good Laboratory Practices, Good Manufacturing Practices, Good Tissue practices, as well as standards set by other accreditation agencies including but not limited to FACT, CAP, and CLIA. 
  • Adhere to ALCOAC++ and cGDocP requirements while accurately performing procedures and maintaining documentation in compliance with SOPs.
  • Document deviations and events, notify supervisor and quality management personnel in timely manner, and assist in investigation of root cause and any required corrective actions.
  • Responsible for aseptic handling of reagents and products to ensure the integrity and sterility of cellular products until final infusion to the patient. Must adhere to special cleaning and gowning requirements for the facility requiring specialized gowning such as masks, sterile jumpsuits, hair and shoe covers. 
Secondary functions:
  • Independently perform calculations to determine cell viability, dilutions, and cell concentrations.  
  • Completes all appropriate logs and trackers.
  • Maintains GMP cleanliness: autoclaving, bleaching liquid waste, removing waste, general cleanliness and organization of the office and facility.
  • Maintains knowledge regarding donor evaluation, screening and testing, labeling and product acceptability and release criteria.
  • Conducts activities to support study plans, and IQ/OQ/PQs.
  • Reviews and provides assistance with change controls, WI, SOPs, study plans, reports, deviations, OOS/OOE, and CAPA’s as directed.
  • Provides improvement and troubleshooting ideas, and executes implementation plans. 
  • Performs routine equipment maintenance and troubleshooting.
  • Prepares high level overviews and leads presentations, as needed.
  • Excellent general lab skills
  • Demonstrated cell culture lab techniques such as cell passaging, cryopreservation, formulation of media, aseptic technique, cell counting, and managing reagents.
  • Ability to work productively and to participate in a highly creative and fast-paced environment.
  • Knowledge of current cGMP.
  • Thorough understanding of qualification/validation activities (process, equipment,etc.).
  • Experience in molecular, cellular, immunological techniques.
Work environment:
  • Typical office environment with moderate noise levels and uses phone, computer, office equipment and supplies on a regular basis.  
  • Grade B/C/D GMP environment with associated facility noise levels and uses cleanroom phone, computer, variety of equipment and reagent/supplies.  
  • While performing the duties of this job, the employee routinely handles blood components and is occasionally exposed to temperatures between 8°C to -196°C, liquid nitrogen, liquid nitrogen vapor, dry ice and carbon dioxide.
Physical demands:
The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
While performing the responsibilities of this job, the employee is required to:
  • Talk and hear.
  • Sit and stand for extended periods of time. 
  • Use his or her hands and fingers, to handle or feel. 
  • Occasionally required to walk, reach with arms and hands, climb or balance, and stoop, kneel, crouch, or crawl, lift, push or pull objects up to 50 pounds. 
  • Undergo color blindness evaluation and vision abilities required for this job include close vision.
  • Don and remove sterile gowning.
Travel required:
  • Travel required between two locations on a daily basis. 
Your profile
Required education and experience
  •  Bachelor’s Degree in Biology, Biochemistry, Biotechnology or other related field.
  •  Four (4) to six (6) years of cell therapy manufacturing experience.
Preferred education and experience
  • Master’s Degree in Biology, Biochemistry, Biotechnology, Healthcare Administration or other related field. 
  • Five (5) years of cell therapy manufacturing experience.
Additional eligibility requirements: None
Work authorization/security clearance requirements
Valid driver’s license and a criminal background check. 
Why us?
What Immatics Offers 
We are a committed and inspired company and cherish the collegial, highly motivated and family-friendly atmosphere within Immatics. Our culture allows for a high level of originality, independent thinking, and initiative. We believe in supporting our employees’ professional and social skills. In addition, we offer:  
  • Competitive Total Rewards package 
  • Base Salary  
  • Annual Bonus  
  • Stock Options – based on position level  
  • 401K plan with company match  
  • Generous Holiday Time  
  • Generous Paid Time Off (PTO) for ALL EMPLOYEES regardless of position level 
  • Full Benefits 
  • Health Insurance  
  • Dental/Vision insurance   
  • Short-Term and Long-Term Disability  
  • Other voluntary insurance (Pet, Legal Shield Identity Theft Protection, Travel Assistant, Accidental Injury and Critical Illness,) 
  • Family Medical Leave 
  • Parental Leave  
  • Employee Assistance Program 
  • Life Insurance policy  
  • Additional Voluntary Life Insurance 
  • Personal time with the CEO in your first 30 days  
  • Collaborative and family environment 
  • Monthly Site meetings with fun team building events 
  • Participation in the annual Houston BioChili Cookoff  
  • Themed Holiday party  
  • Social Community Outreach participation  
  • Development training and planning  
  • Various committees to foster collaboration and involvement within Immatics  
  • Hybrid work schedules (based on position need and supervisor’s approval) 
Notice to Third-Party Recruiters/Staffing Agencies  
Recruitment is managed through Immatics US’ Human Resources department. Resumes will only be accepted from staffing agency/recruiters if there is a signed contract in place. Recruiters are requested to not contact our hiring managers or employees directly to inquire about open positions or to present candidates. In the event a staffing agency/third-party recruiter submits a resume without a contract in place, the candidate submitted will be considered unsolicited and treated as if the candidate submitted their resume directly to Immatics US, and no fee/payment will be paid. Recruiters interested in working with Immatics US can submit their information to, and we will contact you if needed.     
About Us
Immatics combines the discovery of true targets for cancer immunotherapies with the development of the right T cell receptors with the goal of enabling a robust and specific T cell response against these targets.

This deep know-how is the foundation for our pipeline of Adoptive Cell Therapies and TCR Bispecifics as well as our partnerships with global leaders in the pharmaceutical industry. We are committed to delivering the power of T cells and to unlocking new avenues for patients in their fight against cancer.