We are currently seeking a Scientist TCR Research - Preclinical Safety* to support our team in the development and validation of next generation T cell receptors (TCRs) for our innovative Adoptive Cell Therapy (ACT) and TCER® product candidates. You will work within the Immatics Discovery Unit based in Tuebingen (Germany) in the TCR Research department, interacting with colleagues from other research departments in a highly interdisciplinary environment. Your analytical reasoning and action-oriented style as well as your organization and communication skills will contribute to the team’s success.
Your main responsibilities will include but are not limited to the following tasks:
• Characterization, validation and safety testing of TCRs for novel proprietary tumor targets
• Method development in the context of cellular assays (efficacy and safety)
• Management of lab operations and staff
• Contribution to and revision of Standard Operating Procedures (SOPs) and regulatory documents
You hold a PhD degree in Life Sciences with a strong hands-on background in immunology, ideally in the context of cancer immunotherapy. Postdoctoral academic or industry experience is beneficial. You have hands-on experience with cell culture and cell-based functional assays, multicolor flow cytometry and ELISA/ Luminex assays as well as experience in basic molecular biology techniques. You have an advanced level of understanding of biostatistical methods and can apply them to assay design and data evaluation. Experience with primary cell and 3D/ organoid cultures, real-time imaging methods and high-throughput automated liquid handling devices is a plus.
You embrace rapidly changing requirements with an open mind, think outside the box and show a high degree of flexibility in an environment which is marked by a constant striving for excellence. We expect a high degree of independent working, analytical reasoning and excellent communication skills in English.
We are a committed and inspired team and cherish the collegial, highly motivated, and family-friendly atmosphere within Immatics. Our culture allows for a high level of originality, independent thinking, and initiative. We believe in supporting our employees’ professional and social skills: We enable them to join conferences and trainings as well as to enjoy our Immatics benefits – e.g., job bike, job ticket, Health Programs, childcare benefits, relocation allowance, Company summer and winter events.
*We value diversity and inclusion. Immatics N.V. and all Immatics subsidiaries are equal opportunity employers that evaluate qualified applicants without regard to race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law.
Immatics combines the discovery of true targets for cancer immunotherapies with the development of the right T cell receptors with the goal of enabling a robust and specific T cell response against these targets.
This deep know-how is the foundation for our pipeline of Adoptive Cell Therapies and TCR Bispecifics as well as our partnerships with global leaders in the pharmaceutical industry. We are committed to delivering the power of T cells and to unlocking new avenues for patients in their fight against cancer.