Working @ Immatics

Associate Director Clinical Biomarkers/ Companion Diagnostics*

Permanent employee, Full-time · Houston (TX) or remote (US)

Overview
We are currently seeking an Associate Director Clinical Biomarkers/ Companion Diagnostics* to support our team in the research and development of innovative immunotherapeutic products and diagnostics. The position can be located in the US (Houston, TX, or home based).

Your mission
You will support the Immatics therapeutic pipeline by implementing diagnostic solutions to treat the right patient with the right medicine. This role will involve, but is not limited to the following tasks:
 
  • Oversee planning and execution / technical aspects of CDx assay development and validation, clinical implementation of assays, and data analysis in external CDx partnerships;
  • Support and review diagnostic regulatory submissions, e.g., pre-submission packages, Investigational Device Exemptions (IDEs), Study Risk Determinations (SRDs), PMA, De Novo, and 510(k) marketing applications and technical files for CE marking;
  • Lead and/ or support CDx partner evaluation, technical diligence, and selection activities to establish strategic external CDx partnerships with IVD manufacturers and CROs;
  • May act as project lead for joint projects with CDx partners;
  • Help develop the general CDx strategy in a multi-functional team including Immatics’ R&D, clinical, translational, regulatory, commercial, business development, legal, and alliance management functions;
  • May drive implementation of novel biomarker assays as patient screening assays and their further development as CDx (in-house and with partners).
Your profile
  • Advanced degree in Life Sciences, Biochemistry, Molecular Biology, Molecular Medicine, Pharmacy or comparable field; PhD or MS with 5-8 years of relevant experience, including CDx/ IVD development experience in biotech/ pharmaceutical or in vitro diagnostic industry (oncology focus preferred);
  • Strong experience in assay and IVD development and validation in a regulated environment, with broad understanding of guidelines for assay validation;
  • Understanding of US/ EU regulatory requirements for IVD/ CDx development and approval; Familiarity with IVD design control requirements and product development process is preferred;  
  • Knowledge and understanding of technical platforms including qPCR, sequencing technologies (NGS), and IHC. Experience with liquid biopsy preferred;
  • Experience in commercial aspects of companion diagnostics and knowledge of CDx provider landscape is a plus;
  • Experience in performing audits and reviewing vendor audit reports for IVD providers and CROs;
  • Strong project management and organization skills to manage and timely complete deliverables;
  • Proven scientific excellence and ability to evaluate, interpret and present complex scientific data;
  • Excellent communication and presentation skills (written and verbal) in English (German is a plus);
  • Strong motivation to bring innovative diagnostic solutions to the clinic;
  • High level of business awareness.
Why us?
We are a committed and inspired team and cherish the collegial, highly motivated and family-friendly atmosphere within Immatics. Our culture allows for a high level of originality, independent thinking and initiative. We believe in supporting our employees’ professional and social skills. Immatics offers partial subsidized health, dental and vision insurance, 401(k), generous PTO, paid holidays, paid parking, paid short/long term disability/AD&D, life insurance and stock options.
Notice
Recruitment is managed through Immatics US’ Human Resources department. Resumes will only be accepted from staffing agency/recruiters if there is a signed contract in place. Recruiters are requested to not contact our hiring managers or employees directly to inquire about open positions or to present candidates. In the event a staffing agency/third-party recruiter submits a resume without a contract in place, the candidate submitted will be considered unsolicited and treated as if the candidate submitted their resume directly to Immatics US, and no fee/payment will be paid. Recruiters interested in working with Immatics US can submit their information to HR-US@immatics.com, and we will contact you if needed.  
 
Immatics values diversity and inclusion. Immatics N.V. and all Immatics subsidiaries are equal opportunity employers that evaluate qualified applicants without regard to race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law.
About Us
Immatics combines the discovery of true targets for cancer immunotherapies with the development of the right T cell receptors with the goal of enabling a robust and specific T cell response against these targets.

This deep know-how is the foundation for our pipeline of Adoptive Cell Therapies and TCR Bispecifics as well as our partnerships with global leaders in the pharmaceutical industry. We are committed to delivering the power of T cells and to unlocking new avenues for patients in their fight against cancer.