Immatics at the Annual PEGS Europe 2019 (Nov 18-22) in Lisbon, Portugal
Protein & Antibody Engineering Summit
Meet Immatics at the 11th Annual PEGS Europe 2019 (Nov 18-22) in Lisbon, Portugal - the largest European event covering all aspects of protein and antibody engineering.
Thursday, Nov 21, 3.05-3.35pm
Session Insights into Effective Bispecific Mechanisms
TCER® Platform: Targeting of Tumor-Specific HLA Ligands Using T Cell Receptor Bispecifics
Presenter: Sebastian Bunk, Director Immunology
Bispecific T cell-engaging receptors (TCER®) are soluble fusion proteins consisting of an affinity-maturated T cell receptor targeting human leucocyte antigen-bound peptides and an antibody for recruitment of T cells and half-life prolongation. The design of the potent TCER molecules allows redirection of human T cells towards peptide-HLA targets showing highly selective expression in tumor tissue as validated by our target discovery engine, XPRESIDENT®. We present data supporting proof-of-concept of this novel class of T cell engagers.
Wednesday, Nov 20 - Thursday, Nov 21 – Poster Presentations
SESSION B; Location: Rio Pavilion
70B TCER - Design and Characterization of Optimal Scaffolds for Bispecific T Cell Receptor Therapeutics
Presenter: Martin Hofmann, Associate Director Immunology
71B TCER - In Vitro and In Vivo Efficacy of Bispecific T Cell-Engaging Receptors
Presenter: Meike Hutt, Scientist Immunology
72B High-Throughput Peptide-HLA Complex Generation and Kinetic Screenings of TCRs with Peptide-Receptive HLA-A*02:01 Molecules
Presenter: Andreas Moritz, Scientist Immunology
73B TCER - Engineering and Arming of Soluble T Cell Receptors for Targeting of Tumor Specific HLA Ligands
Presenter: Felix Unverdorben, Senior Scientist Immunology
74B TCER Platform - Selection and Validation of Effective and Safe Bispecific T Cell-Engaging Receptor (TCER) Molecules for Cancer Immunotherapy
Presenter: Claudia Wagner, Director Immunology
We’re looking forward to interesting and exciting discussions.
Further information on PEGS Europe – Protein & Antibody Engineering Summit 2019 here.